Similarly, concentrations of urate in the cerebrospinal fluid were also inversely related to risk for PD progression, according to a report

published in Archives of Neurology.

Although the precise mechanism behind the effects of urate on PD progression is not clear, it is possible that the antioxidant may her

oxidative stress that is know' play a role in the destruction dopamine-producing brain ci according to the study's seni author, Michael

Schwarzschl PhD, of MGH-MIND.

Urate can be derived from diet (it is found in foods such organ meats, mushrooms, sl asparagus, cauliflower, sardi herring, as well as

beer and alcoholic beverages), or thrc supplements of the urate-prE inosine, which increases blo of the antioxidant.

However, because high le urate have been linked to risk for hypertension, corona disease, stroke, kidney ston, and gout, the authors cautio

the benefits of elevating ural concentration to very high le must be weighed against po adverse effects.